基因名：
GRK2
产品别名：
ADRBK1； BARK1； BETA-ARK1； GRK2； G protein-coupled receptor kinase 2； G protein-coupled receptor kinase 2； beta-adrenergic receptor kinase 1； adrenergic beta receptor kinase 1； beta-ARK-1； G蛋白偶合受体激酶2； 磷酸化G蛋白偶合受体激酶2； 肾上腺素能受体β激酶(BARK)；
背景信息：
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].
