基因名:
ADRA1A
产品别名:
ADRA1C; ADRA1L1; ALPHA1AAR; ADRA1A; adrenoceptor alpha 1A; adrenoceptor alpha 1A; alpha-1A adrenergic receptor; G protein coupled receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; alpha 1肾上腺素能受体A; 肾上腺素能受体α1A(ADRa1A);
背景信息:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008].