基因名：
ACTL6A
产品别名：
ACTL6； ARPN-BETA； Arp4； BAF53A； INO80K； SMARCN1； ACTL6A； actin like 6A； actin like 6A； actin-like protein 6A； 53 kDa BRG1-associated factor A； BAF complex 53 kDa subunit； BAF53； BRG1-associated factor 53A； INO80 complex subunit K； actin-related protein 4； actin-related protein Baf53a； arpNbeta； hArpN beta； 肌动蛋白样蛋白6A；
背景信息：
The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPn beta), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.
