基因名：
ABCA1
产品别名：
ABC-1； ABC1； CERP； HDLCQTL13； HDLDT1； HPALP1； TGD； ABCA1； ATP binding cassette subfamily A member 1； ATP binding cassette subfamily A member 1； phospholipid-transporting ATPase ABCA1； ATP-binding cassette sub-family A member 1； ATP-binding cassette transporter A1； ATP-binding cassette, sub-family A (ABC1), member 1； cholesterol efflux regulatory protein； membrane-bound； ATP结合盒转运蛋白A1(ABCA1)； 磷酸化腺苷三磷酸结合盒转运体A1； 腺苷三磷酸结合盒转运体A1；
背景信息：
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
