基因名:
KRT78
产品别名:
CK-78; K5B; K78; Kb40; KRT78; keratin 78; keratin 78; keratin, type II cytoskeletal 78; cytokeratin-78; keratin 78, type II; keratin-5b; type-II keratin Kb40; 细胞角蛋白78;
背景信息:
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008]