基因名:
Pilrb1
产品别名:
FDFACT; Fdact; Pilrb; Pilrb1; paired immunoglobin-like type 2 receptor beta 1; paired immunoglobin-like type 2 receptor beta 1; paired immunoglobulin-like type 2 receptor beta; activating receptor PILR-beta; cell surface receptor FDFACT; immunoglobulin-like cell surface receptor FDFACT, activating counterpart; 细胞表面受体PILRβ;
背景信息:
Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.