基因名：
LONRF2
产品别名：
RNF192； LONRF2； LON peptidase N-terminal domain and ring finger 2； LON peptidase N-terminal domain and ring finger 2； LON peptidase N-terminal domain and RING finger protein 2； RING finger protein 192； neuroblastoma apoptosis-related protease； 环指蛋白192；
背景信息：
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. LONRF2 is a 754 amino acid protein containing one LON domain, one RING-type zinc finger and six TPR repeats. Two isoforms of LONRF2 are produced by alternative splicing events. The gene encoding LONRF2 maps to human chromosome 2q11.2 and mouse chromosome 1 B.
