基因名:
Ankrd9
产品别名:
2500003O20Rik; Ankrd9; ankyrin repeat domain 9; ankyrin repeat domain 9; ankyrin repeat domain-containing protein 9; 锚蛋白重复结构域蛋白9;
背景信息:
ANKRD9 is a 317 amino acid protein that contains three ANK repeats. Encoded by a gene that maps to human chromosome 14q32.31, ANKRD9 is conserved in chimpanzee, dog, cow, mouse, rat and zebrafish. Hepatic mRNA levels of ANKRD9 are repressed by both thyroid hormone (T(3)) and fasting, and re-elevate by feeding after fasting. ANKRD9 mRNA levels also decrease in response to apoptosis. Localizing to cytoplasm, ANKRD9 may be involved in intracellular lipid accumulation and lipid metabolism. ANKRD9 may also function as a molecular chaperone