基因名:
SPANXD
产品别名:
CT11.3; CT11.4; SPANX-C; SPANX-D; SPANX-E; SPANXC; SPANXE; dJ171K16.1; SPANXD; SPANX family member D; SPANX family member D; sperm protein associated with the nucleus on the X chromosome D; Cancer/testis antigen 11.3; Cancer/testis-associated protein CTp11; Nuclear-associated protein SPAN-Xc; SPANX family, member E; Sperm protein associated with the nucleus on the X chromosome C; cancer/testis antigen 11.4; cancer/testis antigen family 11, member 4; nuclear-associated protein SPAN-Xd; nuclear-associated protein SPAN-Xe; sperm protein associated with the nucleus, X chromosome, family member D; sperm protein associated with the nucleus, X chromosome, family member E; 癌/睾丸抗原11.4;
背景信息:
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014]