基因名：
BRINP2
产品别名：
DBCCR1L2； FAM5B； BRINP2； BMP/retinoic acid inducible neural specific 2； BMP/retinoic acid inducible neural specific 2； BMP/retinoic acid-inducible neural-specific protein 2； DBCCR1-like protein 2； DBCCR1-like2； bone morphogenetic protein/retinoic acid inducible neural-specific 2； bone morphogenic protein/retinoic acid inducible neural-specific 2； family with sequence similarity 5, member B； protein FAM5B； FAM5B蛋白；
背景信息：
BRINP2 is a 783 amino acid secreted protein that belongs to the FAM5 family. Existing as two alternatively spliced isoforms, BRINP2 is encoded by a gene that maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
