基因名：
LRFN2
产品别名：
FIGLER2； KIAA1246； SALM1； LRFN2； leucine rich repeat and fibronectin type III domain containing 2； leucine rich repeat and fibronectin type III domain containing 2； leucine-rich repeat and fibronectin type-III domain-containing protein 2； fibronectin type III, immunoglobulin and leucine rich repeat domains 2； synaptic adhesion-like molecule 1； 神经突触粘附样分子1；
背景信息：
LRFN2 is a 789 amino acid single-pass type I membrane protein belonging to the LRFN family. Encoded by a gene that maps to human chromosome 6p21.2, LRFN2 is moderately expressed in brain, spleen and testis. LRFN2 contains one fibronectin type-III domain, one Ig-like (immunoglobulin-like) domain and six LRR (leucine-rich) repeats. LRFN2 promotes neurite outgrowth in hippocampal neurons, enhances cell surface expression of two NMDA receptor subunits, NMDAΩ1 and NMDAé1, and may play a role in redistributing PSD-95 to cell periphery. LRFN2 forms heteromeric complexes with LRFN1, LRFN3, LRFN4 and LRFN5, and is capable of forming homomeric complexes, but not across cell junctions.
