基因名：
BLOC1S4
产品别名：
BCAS4L； BLOS4； CNO； BLOC1S4； biogenesis of lysosomal organelles complex 1 subunit 4； biogenesis of lysosomal organelles complex 1 subunit 4； biogenesis of lysosome-related organelles complex 1 subunit 4； BLOC-1 subunit 4； biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino； cappuccino homolog； protein cappuccino homolog； Cappuccino蛋白；
背景信息：
Biogenesis of lysosome-related organelles complex-1 (BLOC-1) is a multisubunit protein necessary for biogenesis of specialized organelles of the endosomal-lysosomal system (such as melanosomes and platelet-dense granules). The complex consists of coiled-coil-forming proteins Snapin, Pallidin, Cappuccino, Muted, BLOS1, BLOS2, and BLOS3. The localization of these proteins varies as they can be cytoplasmic, peripheral membrane bound or anchored to the vesicular membrane.Cappuccino, a primarily cytoplasmic protein, plays a role in the development of melanosomes, platelet-dense granules and other lysosome-related organelles. It interacts primarily with pallidin and Muted and has been implicated as an actin-nucleation factor that may play a role in crosstalk between microfilaments and microtubules.
