基因名：
Ifi202b
产品别名：
Ifbip-1； Ifi202； Ifi202a； Ifi202c； p202； Ifi202b； interferon activated gene 202B； interferon activated gene 202B； interferon-activable protein 202； Interferon-activatable protein 202a (Ifi-202a) (Interferon-inducible protein p202a)； ifi-202； interferon activated gene 202A； interferon-inducible protein p202； lupus susceptibility protein p202； γ干扰素诱导蛋白202；
背景信息：
IFI-202 is a primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFkB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-g in HL60 cells. At least four of the Gene 200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.
