基因名：
HIVEP1
产品别名：
CIRIP； CRYBP1； GAAP； MBP-1； PRDII-BF1； Schnurri-1； ZAS1； ZNF40； ZNF40A； HIVEP1； HIVEP zinc finger 1； HIVEP zinc finger 1； zinc finger protein 40； cirhin interaction protein； gate keeper of apoptosis-activating protein； human immunodeficiency virus type I enhancer binding protein 1； major histocompatibility complex binding protein 1； positive regulatory domain II binding factor 1；
背景信息：
This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
