靶标：
TAS2R45
产品别名：
GPR59； T2R45； ZG24P； TAS2R45； taste 2 receptor member 45； taste 2 receptor member 45； taste receptor type 2 member 45； G-protein coupled receptor 59； taste receptor, type 2, member 45；
背景信息：
function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
