靶标:
Dcaf12l2
产品别名:
A130007F10Rik; Wdr40c; Dcaf12l2; DDB1 and CUL4 associated factor 12-like 2; DDB1 and CUL4 associated factor 12-like 2; DDB1- and CUL4-associated factor 12-like protein 2; WD repeat domain 40C; WD repeat-containing protein 40C; WD40 domain;
背景信息:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein. [provided by RefSeq, May 2010],