靶标：
Shisa7
产品别名：
ckamp59； Shisa7； shisa family member 7； shisa family member 7； protein shisa-7； GABA(A) receptor auxiliary subunit Shisa7； cysteine-knot AMPAR-modulating protein 59； cystine-knot AMPAR modulating protein of 59 kDa； shisa homolog 7； SHISA7蛋白；
背景信息：
Shisa7, a single-passing transmembrane protein, localizes at GABAergic inhibitory synapses and interacts with GABA-A receptors. Shisa7 controlled receptor abundance at synapses and sped up the channel deactivation kinetics. Shisa7 also potently enhanced the action of diazepam, a classic benzodiazepine, on GABA-A receptors. Genetic deletion of Shisa7 selectively impaired GABAergic transmission and diminished the effects of diazepam in mic
