靶标:
RAET1L
产品别名:
RAET1H; ULBP6; RAET1L; retinoic acid early transcript 1L; retinoic acid early transcript 1L; UL16-binding protein 6; UL16 binding protein 6; retinoic acid early transcript 1H; retinoic acid early transcript 1L protein;
背景信息:
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing.