靶标:
NLRP13
产品别名:
CLR19.7; NALP13; NOD14; PAN13; NLRP13; NLR family pyrin domain containing 13; NLR family pyrin domain containing 13; NACHT, LRR and PYD domains-containing protein 13; NACHT, LRR and PYD containing protein 13; NACHT, leucine rich repeat and PYD containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13; NLRP13蛋白;
背景信息:
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.