靶标:
Nlrp14
产品别名:
4921520L01Rik; GC-LRR; Nalp-iota; Nalp14; Nalp14l; Nlrp14; NLR family, pyrin domain containing 14; NLR family, pyrin domain containing 14; NACHT, LRR and PYD domains-containing protein 14; NACHT, leucine rich repeat and PYD containing 14; RNI-like protein; germ-cell specific leucine rich repeat NTPase; NLRP14蛋白;
背景信息:
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.