靶标:
Mplkip
产品别名:
2810021B07Rik; C330007M08Rik; Ttdn1; Mplkip; M-phase specific PLK1 intereacting protein; M-phase specific PLK1 intereacting protein; M-phase-specific PLK1-interacting protein; TTD non-photosensitive 1 protein homolog;
背景信息:
The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.