靶标：
RDH8
产品别名：
PRRDH； SDR28C2； RDH8； retinol dehydrogenase 8； retinol dehydrogenase 8； retinol dehydrogenase 8； photoreceptor outer segment all-trans retinol dehydrogenase； retinol dehydrogenase 8 (all-trans)； short chain dehydrogenase/reductase family 28C member 2；
背景信息：
All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.
