靶标：
COQ2
产品别名：
CL640； COQ10D1； MSA1； PHB:PPT； COQ2； coenzyme Q2, polyprenyltransferase； coenzyme Q2, polyprenyltransferase； 4-hydroxybenzoate polyprenyltransferase, mitochondrial； 4-HB polyprenyltransferase； 4-hydroxybenzoate decaprenyltransferase； PHB:polyprenyltransferase； coenzyme Q2 4-hydroxybenzoate polyprenyltransferase； coenzyme Q2 homolog, prenyltransferase； para-hydroxybenzoate-polyprenyltransferase, mitochondrial； 线粒体COQ2；
背景信息：
This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009],
