靶标：
TIMM13
产品别名：
TIM13； TIM13B； TIMM13A； TIMM13B； ppv1； TIMM13； translocase of inner mitochondrial membrane 13； translocase of inner mitochondrial membrane 13； mitochondrial import inner membrane translocase subunit Tim13； mitochondrial import inner membrane translocase subunit Tim13B； translocase of inner mitochondrial membrane 13 homolog；
背景信息：
Timm13 is a mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. It acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
