靶标:
FBXO46
产品别名:
20D7-FC4; FBXO34L; Fbx46; FBXO46; F-box protein 46; F-box protein 46; F-box only protein 46; FBXO46蛋白;
背景信息:
Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],