靶标:
Alppl2
产品别名:
Akp5; Alpg; C77216; D1Ertd816e; EAP; Alppl2; alkaline phosphatase, placental-like 2; alkaline phosphatase, placental-like 2; alkaline phosphatase, germ cell type; alkaline phosphatase 5; embryonic alkaline phosphatase; embryonic-type alkaline phosphatase; 胎盘碱性磷酸酶样蛋白2(ALPPL2);
背景信息:
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015],