靶标:
LRRN2
产品别名:
FIGLER7; GAC1; LRANK1; LRRN5; LRRN2; leucine rich repeat neuronal 2; leucine rich repeat neuronal 2; leucine-rich repeat neuronal protein 2; fibronectin type III, immunoglobulin and leucine rich repeat domain 7; glioma amplified on chromosome 1 protein; leucine rich and ankyrin repeats 1; leucine rich repeat neuronal 5; leucine-rich repeat neuronal protein 5; 富含亮氨酸重复神经元5;
背景信息:
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],