靶标:
SON
产品别名:
BASS1; C21orf50; DBP-5; NREBP; SON3; TOKIMS; SON; SON DNA and RNA binding protein; SON DNA and RNA binding protein; protein SON; Bax antagonist selected in Saccharomyces 1; NRE-binding protein; SON DNA binding protein; negative regulatory element-binding protein;
背景信息:
This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants.