靶标:
GUCY1B2
产品别名:
GC-SB2; GUCY1B2; guanylate cyclase 1 soluble subunit beta 2 (pseudogene); guanylate cyclase 1 soluble subunit beta 2 (pseudogene); guanylate cyclase 1 solube subunit beta 2 (pseudogene); guanylate cyclase 1, soluble, beta 2 (pseudogene); 鸟苷酸环化酶/GCS-β-2/GCS-β2;
背景信息:
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.