靶标:
tptep2-csnk1e
产品别名:
CKIe; CKIepsilon; LOC400927-csnk1e; ck1-epsilon; ck1epsilon; csnk1e; hckie; tptep2-csnk1e; TPTEP2-CSNK1E readthrough; TPTEP2-CSNK1E readthrough; casein kinase I isoform epsilon; casein kinase I; casein kinase 1 epsilon;
背景信息:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation.