靶标：
MRGPRX1
产品别名：
GPCR； MGRG2； MRGX1； SNSR4； MRGPRX1； MAS related GPR family member X1； MAS related GPR family member X1； mas-related G-protein coupled receptor member X1； G protein-coupled receptor MRGX1； G protein-coupled receptor SNSR3； MAS-related GPR, member X1； Mas-related G protein-coupled receptor G2； sensory neuron-specific G-protein coupled receptor 3/4； G蛋白偶联受体MRGX1；
背景信息：
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
