靶标:
IL27
产品别名:
IL-27; IL-27A; IL27A; IL27p28; IL30; p28; IL27; interleukin 27; interleukin 27; interleukin-27 subunit alpha; IL-27 p28 subunit; IL-27 subunit alpha; IL-27-A; IL27-A; interleukin-30; 白介素27A(IL27A); 白细胞介素27;
背景信息:
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008],