靶标：
Nlrp10
产品别名：
6430548I20Rik； Nalp10； Napl10； PAN5； Pynod； Nlrp10； NLR family, pyrin domain containing 10； NLR family, pyrin domain containing 10； NACHT, LRR and PYD domains-containing protein 10； NACHT, LRR and PYD containing protein 10； NACHT, leucine rich repeat and PYD containing 10； NACHT/LRR/pyrin domain-containing protein 10； neuronal apoptosis inhibitor protein 10； 富含亮氨酸重复结构域蛋白10；
背景信息：
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
