靶标:
NCOA7
产品别名:
ERAP140; ESNA1; NCOA7-AS; Nbla00052; Nbla10993; TLDC4; dJ187J11.3; NCOA7; nuclear receptor coactivator 7; nuclear receptor coactivator 7; nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; TBC/LysM-associated domain containing 4; estrogen nuclear receptor coactivator 1; estrogen receptor associated protein 140 kDa; putative protein product of Nbla00052; putative protein product of Nbla10993; 核受体共激活因子7;
背景信息:
function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,