靶标：
TP53RK
产品别名：
BUD32； C20orf64； GAMOS4； Nori-2； Nori-2p； PRPK； TPRKB； dJ101A2； TP53RK； TP53 regulating kinase； TP53 regulating kinase； EKC/KEOPS complex subunit TP53RK； atypical serine/threonine protein kinase TP53RK； p53-related protein kinase； TP53调节激酶；
背景信息：
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6A37 in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.
