靶标：
Hscb
产品别名：
AI325508； AW049829； Hsc20； Hscb； HscB iron-sulfur cluster co-chaperone； HscB iron-sulfur cluster co-chaperone； iron-sulfur cluster co-chaperone protein HscB； HscB iron-sulfur cluster co-chaperone homolog； J-type co-chaperone HSC20； iron-sulfur cluster co-chaperone protein HscB, mitochondrial； HSCB蛋白；
背景信息：
This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
