靶标:
TP53INP1
产品别名:
SIP; TP53DINP1; TP53INP1A; TP53INP1B; Teap; p53DINP1; TP53INP1; tumor protein p53 inducible nuclear protein 1; tumor protein p53 inducible nuclear protein 1; tumor protein p53-inducible nuclear protein 1; p53-dependent damage-inducible nuclear protein 1; p53-inducible p53DINP1; stress-induced protein; p53诱导核蛋白1;
背景信息:
function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,