靶标:
SLC25A21
产品别名:
MTDPS18; ODC; ODC1; SLC25A21; solute carrier family 25 member 21; solute carrier family 25 member 21; mitochondrial 2-oxodicarboxylate carrier; oxodicarboxylate carrier; solute carrier family 25 (mitochondrial oxoadipate carrier), member 21; solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21; 溶质载体家族蛋白25成员A21;
背景信息:
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004],