靶标：
ORAI1
产品别名：
CRACM1； IMD9； ORAT1； TAM2； TMEM142A； ORAI1； ORAI calcium release-activated calcium modulator 1； ORAI calcium release-activated calcium modulator 1； calcium release-activated calcium channel protein 1； calcium release-activated calcium modulator 1； protein orai-1； transmembrane protein 142A； 嗅觉受体ai1；
背景信息：
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
