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锌指蛋白ZGPAT抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Anti-ZGPAT
Anti-zinc finger CCCH-type and G-patch domain containing Antibody
靶标:

ZGPAT


产品别名:

GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP; ZGPAT; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type with G patch domain-containing protein; g patch domain-containing protein 6; zinc finger CCCH domain-containing protein 9; zinc finger and G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; 锌指蛋白ZGPAT;


背景信息:
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
 
 
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