靶标:
TRAF7
产品别名:
CAFDADD; RFWD1; RNF119; TRAF7; TNF receptor associated factor 7; TNF receptor associated factor 7; E3 ubiquitin-protein ligase TRAF7; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; ring finger and WD repeat domain 1; 肿瘤坏死因子受体相关因子7;
背景信息:
TNF receptor associated factor 7(TRAF7) Homo sapiens Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004],