靶标:
STN1
产品别名:
AAF-44; AAF44; OBFC1; RPA-32; bA541N10.2; STN1; STN1 subunit of CST complex; STN1 subunit of CST complex; CST complex subunit STN1; STN1, CST complex subunit; alpha accessory factor 44; oligonucleotide/oligosaccharide binding fold containing 1; oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; suppressor of cdc thirteen homolog; α辅助因子44;
背景信息:
OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication. OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130).