靶标:
Tchp
产品别名:
A930031F18Rik; AV279199; Tchp; trichoplein, keratin filament binding; trichoplein, keratin filament binding; trichoplein keratin filament-binding protein; mitochondrial protein with oncostatic activity; mitostatin; 抑癌蛋白TCHP;
背景信息:
function:May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.,similarity:Belongs to the TCHP family.,subunit:Interacts specifically with keratin proteins including, KRT5, KRT6A, KRT8, KRT14, KRT16 and KRT18.,