靶标：
Dock8
产品别名：
1200017A24Rik； 5830472H07Rik； A130095G14Rik； AI461977； Dock8； dedicator of cytokinesis 8； dedicator of cytokinesis 8； dedicator of cytokinesis protein 8； 胞质分裂蛋白8奉献者；
背景信息：
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
