靶标：
Pus10
产品别名：
2810013G11Rik； 4933435A13Rik； AU014648； C77560； Ccdc139； Pus10； pseudouridylate synthase 10； pseudouridylate synthase 10； tRNA pseudouridine synthase Pus10； coiled-coil domain containing 139； coiled-coil domain-containing protein 139； psi55 synthase； putative tRNA pseudouridine synthase Pus10； tRNA pseudouridine 55 synthase； tRNA pseudouridylate synthase； tRNA-uridine isomerase； 卷曲螺旋结构域蛋白139；
背景信息：
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009],
