靶标:
Hexim2
产品别名:
4933402L21Rik; Hexim2; hexamethylene bis-acetamide inducible 2; hexamethylene bis-acetamide inducible 2; protein HEXIM2; hexamthylene bis-acetamide inducible 2; HEXIM2蛋白;
背景信息:
This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],