靶标:
Ubac2
产品别名:
1190008A14Rik; AW554959; Phgdhl1; Ubac2; ubiquitin associated domain containing 2; ubiquitin associated domain containing 2; ubiquitin-associated domain-containing protein 2; UBA domain-containing protein 2; phosphoglycerate dehydrogenase like 1; phosphoglycerate dehydrogenase-like protein 1;
背景信息:
Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6.