靶标:
Gnpda2
产品别名:
4921523I18Rik; 4933412A11Rik; BB189630; GNPDA; Gnp2; Sb52; mKIAA4008; Gnpda2; glucosamine-6-phosphate deaminase 2; glucosamine-6-phosphate deaminase 2; glucosamine-6-phosphate isomerase 2; GNPDA 2; glcN6P deaminase 2; oscillin; 葡萄糖6-磷酸脱氨酶2;
背景信息:
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.