靶标:
Henmt1
产品别名:
4921515J06Rik; Hen1; mHEN1; Henmt1; HEN1 methyltransferase homolog 1 (Arabidopsis); HEN1 methyltransferase homolog 1 (Arabidopsis); small RNA 2'-O-methyltransferase; HEN1甲基转移酶同源蛋白1;
背景信息:
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.