靶标：
Anp32e
产品别名：
2810018A15Rik； AI047746； AI326868； CPD1； LANP-L； LANPL； mLANP-L； Anp32e； acidic (leucine-rich) nuclear phosphoprotein 32 family, member E； acidic (leucine-rich) nuclear phosphoprotein 32 family, member E； acidic leucine-rich nuclear phosphoprotein 32 family member E； LANP-like protein； cerebellar postnatal development protein 1； 富含亮氨酸样酸性核蛋白；
背景信息：
Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A. Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
